Low-load exercise program and platelet-rich plasma for intrasubstance tear in lateral elbow tendinopathy: protocol for a double-blinded randomized clinical trial

Background: Lateral elbow tendinopathy (LET) is one of the most common musculoskeletal conditions. Treatment includes a series therapeutic alternatives. However, resolution takes nearly 24 months. Platelet-rich plasma (PRP) an effective option, especially when tendon presents intrasubstance tear (IST). It unknown what type rehabilitation plan more after this treatment. Aim: To perform study protocol double-blinded, randomized clinical trial to determine efficacy specific low-load exercise program in patients with LET and IST treatment PRP under US-guided Methods: A single-center, parallel-controlled, randomized, phase III was pro-posed. Patients over 18 years-old diagnosed treated will be selected. Two arms allocated ratio 1:1 (low-load vs. conventional program). The principal outcome reduction size. Secondary outcomes include Patient-Rated Tennis Elbow Evaluation score, visual analogue scale, handgrip at baseline, 3, 6, 12 months follow-up. Statistical tests 2-sided t-test alpha level (significance level) 0.05. Discussion: intervention aims significantly reduce size improve pain functionality PRP. We proposed first studies literature that considered detailed standardized applied these patients. result could used speed up save time money, help evaluate guidelines, patients' athletes' quality life.